The Tottenham and England midfielder has until March 5 to answer the charge after posting the video on Snapchat.
Dele Alli was charged with misconduct by the Football Association (FA) over his contentious coronavirus video.
The Tottenham and England midfielder posted a movie on Snapchat from an airport when wearing a face mask, apparently suggesting an Asian guy at the terminal could be infected with the virus.
An FA statement read:”It is alleged that the Tottenham Hotspur midfielder’s article breaches FA Rule E3(1) because it was insulting and/or improper and/or brought the game into disrepute.
“It is further alleged that the article constitutes an”Aggravated Breach”, which is described in FA Rule E3(2), as it included a reference, whether express or implied, to race or color and/or ethnic origin and/or nationality.
“He’s until Thursday, March 5, 2020 to supply a response.”
Alli has already apologised for the movie, using the Chinese social networking site Weibo.
“I just wanted to apologise on my behalf for the video I posted on Snapchat yesterday. It was not funny and I realised that instantly and took it down,” 23-year-old Alli said.
“I let myself down and the club. I don’t want you guys to have this impression of me because it was not funny and I realised that right away and down it.
“It is not something which needs to be joked about. I am sending all my love and all of my thoughts and prayers with everyone in China.”
If found guilty, Alli would face a suspension from the FA.
Bernardo Silva was banned for one game after his tweet about Manchester City team-mate Benjamin Mendy earlier in the summer, after admitting a breach of the exact same FA Rule E3.
An aggravated violation of the FA’s discrimination principles carries a minimum ban of six games.
Tottenham have two matches before Alli’s deadline of March 5, with Wolves and Norwich travelling to north London in the Premier League and FA Cup respectively.
Then they face further league fixtures with Burnley, Manchester United and West Ham, in addition to their Champions League last 16 second-leg match with RB Leipzig.
Spurs boss Jose Mourinho has defended Alli, implying young players such as Alli have to be careful on social networking.
“I talked with him about that but it was rather a Simple conversation because he was very sorry about — let us say, the error — but it wasn’t his intention to hurt or offend,” Mourinho told reporters
“He instantly regretted and recognized it was a youthful generation mistake and he apologised.
“I have a son in exactly the exact same age as Dele and lots of the players.
“I understand social media is for his creation but when you’re a public person like footballers are, they must know and they must be very, very cautious.
“Dele is an excellent guy. The last thing that he is anything connected with racism.”